Assigned Proteins for Student Work:
In order to facilitate working with some of the databases we'll use in the course, I've assigned each of you a specific member of the 6 enzyme classes to work with. These proteins will be the subject of your two presentations AND will provide you with concrete structures and chemistries with which to study for the exams.
Abby:
1) Saccharomyces cerevisiae Homoserine dehydrogenase (1ebf) (1.1.1.3)
2) Homo sapiens Basic fibroblast growth factor receptor 1 (3ggl) (2.7.10.1)
3) Homo sapiens DEAD-box RNA helicase (3b7g) (3.6.4.13)
4) Burkholderia cepacia Dialkylglycine decarboxylase (1z3z) (4.1.1.64)
5) Cytophaga hutchinsonii Dipeptide epimerase (3q45) (5.5.1.7)
6) Salmonella enterica Acetyl-CoA Synthetase (2p2f) (6.2.1.1)
Craig:
1) Thermus thermophilus Lipoamide dehydrogenase (2ygu) (1.8.1.4)
2) Pseudomonas aeruginosa Exotoxin A (1xk9) (2.4.2.36)
3) Homo sapiens Beta-secretase 1 (3tpl) (3.4.23.46)
4) Synechococcus elongatus RUBISCO (1rbl) (4.1.1.39)
5) Thermotoga maritima Glucose-6-Phosphate Isomerase (2q8n) (5.3.1.9)
6) Mycobacterium smegmatis Cysteinyl-tRNA synthetase (3c8z) (6.3.1.13)
Kennon:
1) Methylobacterium extorquens Methanol dehydrogenase (1h4i) (1.1.2.7)
2) Gallus gallus c-Src Tyrosine kinase SH3 domain (1rlp) (2.7.10.2)
3) Xanthobacter autotrophicus Haloalkane dehydrogenase (1hde) (3.8.1.5)
4) Pisum sativum Beta-carbonic anhydrase (1ekj) (4.2.1.1)
5) Trypanosoma bruceii Thiamine phosphate synthase (2y6z) (5.3.1.1)
6) Pseudomonas aeruginosa 3-methylcrotonyl-CoA carboxylase (3u9t) (6.4.1.4)
Kevin:
1) Staphylococcus aureus Enoyl-[acyl-carrier-protein] reductase (3gnt) (1.3.1.10)
2) Escherichia coli Molybdopterin biosynthesis MoeA Protein (1fc5) (2.10.1.1)
3) Pseudomonas aeruginosa Beta-lactamase (1e3u) (3.5.2.6)
4) Escherichia coli Ethanolamine ammonia lyase (3abs) (4.3.1.7)
5) Trypanosoma bruceii Phosphoglycerate mutase (3nvl) (5.4.2.1)
6) Archaeoglobus fulgidus ATP-Dependent ligase (3gde) (6.5.1.1)
Laura:
1) Mycobacterium tuberculosis Alanine dehydrogenase (2vhy) (1.4.1.1)
2) Oryctolagus cuniculus Glycogen phosphorylase B (3gpb) (2.4.1.1)
3) Shigella dysenteriae Shiga toxin (1dm0) (3.2.2.22)
4) Rattus norvegicus Selenocysteine lyase (3a9x) (4.4.1.16)
5) Nocardia farcinica Maleate Cis-Trans Isomerase (2xec) (5.2.1.1)
6) Thermus thermophiles Phenylalanyl-tRNA synthetase (3teh) (6.1.1.20)
Paisley:
1) Xanthomonas campestris Tryptophan 2,3-dioxygenase (2nw7) (1.13.11.11)
2) Bacillus anthracis Dihydropteroate synthase (3h23) (2.5.1.15)
3) Meleagris gallopavo Egg white lysozyme (2lz2) (3.2.1.17)
4) Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C (3ea1) (4.6.1.13)
5) Staphylococcus aureus Alanine racemase (4a3q) (5.1.1.1)
6) Yersinia pestis D-alanine-D-alanine ligase (3v4z) (6.3.2.4)
|
