General Chemistry II Course
Competencies
Lsn 7: Enzymes as Drug Targets II (Enzyme
Kinetics)
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Michaelis-Menton kinetics
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Write equilibria associated with enzyme-substrate interactions
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Understand how reaction order changes with substrate concentration
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Be able to use the Lineweaver-Burke relationship to calculate Vmax,
turnover number, and KM
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Understand the significance of KM; understand the relation of
KM to enzyme-substrate complex stability and to maximum reaction
rate