Lsn 5: Proteins as Drug Targets II  (Protein structure)

• Understand how peptide bonds are formed and draw appropriate resonance structure to explain peptide bond geometry
• Know the primary structure of peptides
• Understand protein secondary structure; draw diagrams to represent the underlying reason for the formation of alpha helices and beta sheets
• Understand the various types of interactions that can occur between side chains; draw appropriate diagrams and clearly discuss these
• Understand protein tertiary and quaternary structures
• Understand the underlying reasons for the structure of globular proteins
• Clearly discuss and diagram prions formation process and their relevance
• Outline major functions of proteins in the human body