Course Instructor: Dr. Jason C. Hurlbert, 301B Sims Science Building , Rock Hill, SC  29733    803/323-4928    803/323-2246 (Fax)   

Course Syllabus
Answer Keys
Lecture Notes
Supplemental Materials:
Problem Sets, Reading Materials
CHEM 106: General Chemistry 2 (Spring 2019, Section 001)

Course Specifics:

Instructor:        Dr. Jason C. Hurlbert
                          Office:  Sims 301B
                          Office hours:  M 10:30-11:30, W 2:00-3:00 and by appointment
                          Phone:  (803) 323-4928

Meeting Times:

Lecture:    Tuesday and Thursday, 3:30-4:45PM, Sims 105 

Textbook:    Biochemistry by T.A. Brown

Course Outline and Objectives:

We will cover the following topics during the semester:

  • Chemical concepts as they relate to biological systems
  • Chemical Reactivity
  • Intramolecular forces
  • The chemistry of the essential molecules for life: lipids, amino acids and sugars
    • Specifically: How these molecules are made, how they react and how they interact with other molecules found in the cell.
  • Molecular Biology (The relationship between biology and chemistry)
  • Enzymology
  • Metabolic pathways and the chemistry behind them

Along the way, I hope to show you how important the field of chemistry is in everyday life. We will spend the initial part of the course firming up material covered in General Chemistry I, then move into the chemical basis for many biological processes, and finish by studying specific metabolic pathways from a chemical point of view. In addition, the course will serve to help build your critical thinking skills and develop effective study habits, traits you'll need regardless of your chosen career goals.

CHEM106 Section 001 Spring 2019 Tentative Course Schedule

(Modified Sunday, October 21, 2018)

Note:  This schedule will change as necessary. 


Assignments given in the "Assignments" column of the table below should be completed after the lecture but are not due unless they are given in red and are called "Problem Sets"

You should do the problems after lecture so that you can be confident in your abilities

Once again, only things labeled Problem Sets should be turned in on paper to me at the start of class on the date given



Material Covered

Assignments and Supplemental Materials for Review


8 January

Course Introduction and Intermolecular forces


10 January

Introduction to thinking about biology chemically


15 January

Weak Acid-Base Chemistry

ChemTeam Webpage on Acids and Bases

I strongly suggest you review the problems on weak acids and weak bases


17 January


22 January

Organic Chemistry 1: 

Hydrocarbon naming and Functional Groups

You must start memorizing the functional groups IMMEDIATELY!

Supplemental: Organic Cheimstry Functional Group Chart


24 January


29 January

Organic Chemistry 2:

Common Reactions: Nucleophilic substitution, General Acid-Base catalysis and Condensation reactions

Problem Set 1 Due


31 January


5 February

Review for Test 1


7 February

Test 1


12 February

Amino Acids: 

Structure and Behaviour

Start memorizing the core amino acid structure, side chains and pKa values NOW!

Biochemistry Chapter 3.1 and Chapter 3.2

You should be able to answer the first 10 problems of Chapter 3 after this lecture


14 February

Proteins 1: Structure and Folding

Biochemistry Chapter 3.3 and 3.4

You should be able to do all of the problems at the end of Chapter 3


19 February

No Class Meeting


21 February

Proteins 2: Enzymes

Biochemistry Chapter 7

Supplemental: Enzyme Kinetics

4.1 -

Supplemental: Enzyme Kinetics

4.2.7 -

Handout on using a Texas Instruments graphing calculator to analyze kinetic data

26 February

Supplemental: Enzyme Kinetics 4.3 -

Supplemental: Enzyme Kinetics 4.3 -

Upon completion of this lecture you should be able to complete the first 21 questions and the back of Biochemistry Chapter 7



28 February

Proteins 4:  Enzyme Control and Active Sites

Problem Set 2 Due

Supplemental: Enzyme function and regulation


5 March

Review for Test 2

7 March

Test 2


12 March

Spring Break - No Class

14 March

Spring Break - No Class


19 March

Reaction Mechanisms: Why do enzymes and substrates react the way they do?

Case Study 1:Chymotrypsin

Case Study 2:Alcohol dehydrogenase


21 March

Quiz 3 (Take Home) Given Out


26 March

Lipids and Biological Membranes

Biochemistry Chapter 5

You should be able to complete all Biochemistry Chapter 5 Problems: 1 - 24 and all Short Answer Questions on page 106

28 March


Biochemistry Chapter 6

You should be able to complete all Biochemistry Chapter 6 Problems: 1 - 20 and all Short Answer Questions on page 123


2 April


Biochemistry Chapter 8

Take Home Quiz 3 Due


4 April

You should be able to complete all Biochemistry Chapter 8 Problems: 1 - 20 and all Short Answer Questions on page 177


9 April

Test 3


11 April

Cell Signalling


16 April


Problem Set 3 Due


18 April

Final Exam Review

Grading for the Course

We will not have weekly homework assignemnts as you may have had in other courses, but after each bok chapte, I will recommend that you be able to answer specified questions at the end of the chapter. These end of chapter questions will not be picked up, but shold be completed to help you preparefor the tests and final exam. There will be four Assigned Problem sets that will be collected on the dates given on the main course webpage. These problem sets can be downloaded from the "Supplemental materials: Problem Sets and Reading Materials" page of the course website. Please feel free to work in groups on these problems. However, make sure that you understand how these problems are solved as you may be required to present the solutions to the class during the recitation sections.

There will be several pop quizzes throughout the semester. You should count on having a pop quiz a week to keep you on track with material. Each pop quiz will be 10 minutes and worth 10 points unless otherwise stared at the time of the quiz.

Test 1 (7 February, 2019)
Test 2 (7 March, 2019)
Test 3 (9 April, 2019)
• Each test will have a value of 100 points

Final Exam - Friday, 26 April at 3:00PM
The final exam is cumulative and you must make at least a 50% on the exam to pass the course.
• The final exam will cover the entire course and will have a value of 200 points

Total Possible Points

120 points: Quizzes: 12 @ 10 points each
300 points: Tests: 3 @ 100 points each
200 points: Final Exam
200 points: Homework: 4 problem sets @ 50 points each
820 Total possible points for the course


A  :  90 - 100% (738-820 pts)
B+:  86 - 89% (705-737 pts)
B  :  77 - 85% (631-704 pts)
C+:  74 - 76% (533-630 pts)
C  :  66 - 73% (541-532 pts)
D  :  56 - 65% (459-540 pts)
F  :  <55% (<458 pts)

CHEM 108 Corequisite

Since the CHEM 106/108 combination represents a General Education requirement, CHEM108 must be completed and passed in order to receive a final grade in CHEM106. Students who do not pass CHEM108 will receive an incomplete in CHEM106 until CHEM108 has been passed.

Technology in the Classroom

Out of respect for everyone in the room, please turn your cellular telephones to ‘Silent’ and (if applicable) mute your laptop computers. Also, laptop computers may only be used for taking notes during the class period, not updating your Facebook page, checking email, tweeting, etc.  Due to the complex nature of many of the subjects discussed during lecture and the frequent use of graphs and figures, it is the instructor's opinion that the best way to take notes is by hand. Students failing to adhere to these rules may be asked to leave should their behavior prove disruptive to the class.  No telephones or laptops may be used during exams or quizzes. You will need to bring a scientific calculator to class for quizzes and exams.

Students with Disabilities/Need of Accommodations for Access:





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