Chemistry 301-001/003/004: Organic Chemistry

Dr. T. Christian Grattan (Office Sims 301B)

Spring 2021 Winthrop University

MWF 12:30-1:45 PM (SIMS 209)

4 Credit hours


Organic Chemistry with Biological Topics, 6th ed., Smith REQUIRED

Molecular Model Kit, ask Dr. Grattan RECOMMENDED

          Computer/Laptop with webcam REQUIRED


My goal for this course is to clearly explain the fundamental concepts of organic chemistry and how they are incorporated into chemical reactions and mechanisms in accordance with departmental objectives. The students should be able to:


  1. Become proficient in organic nomenclature from structure to name and name to structure for the various derivatives emphasized in the course (alkanes, alkenes..etc)
  2. Understand bonding and three-dimensional shape of organic molecules for a better understanding of energetic stability and preferred reactivity.
  3. Identify functional group conversion or transformation given any two of the following: starting material, reagents and products for various chemical reactions and the energy that drives each process.
  4. Become proficient in mechanistic organic chemistry to explain how the reactions are converted to products with emphasis on electron movement arrows, intermediate charge and resonance involvement.
  5. Aromatic compound characteristics and reactivity with emphasis on energetic stability, resonance role in reactions and the various options available to aromatic substitution chemistry.
  6. Evaluate the kinetic and thermodynamic differences in a chemical reaction.
  7. Examine the physical properties of molecules and discuss the reasoning behind the differences.
  8. Develop and design multi-step synthetic processes to perform organic functional group interconversions.
  9. Become proficient in interpreting organic analytical such as NMR, IR and mass spectra.


University Level Competency #1: In this course students will be challenged to think critically and solve problems logically in accordance with ULC #1. This approach will aid in their future courses and help develop better study and work habits.



Virtual Office Hours: M 11:00 AM-11:30 AM, W 11:00-12:00 PM

or by appointment (323-4927 or


While I will be available to answer questions during the virtual office hours or by appointment I will also have a discussion board available for students to ask questions throughout the semester. Other students are encouraged to respond on this discussion board in a helpful or polite manner. I will also monitor the discussion board and contribute along the way.

You will find that this course is different than any other courses you have taken in college. It is therefore important to stay on top of the material and get your questions answered as soon as possible. Please take advantage of my office hours or the discussion board to resolve these problems.  


Attendance: Due to the unique nature of this course, each and every class meeting is important to better understand the material in the text. The students are responsible for all assignments for the course regardless of absence. I will take attendance during any in-person meetings, but will otherwise monitor the blackboard links via tracking.


Homework and Assignments: Problems will be assigned using CONNECT from the text for each chapter for practice. These problems will be graded although I do not limit the number of times you may complete the homework sets prior to the due date. I will also provide a problem set relating to each chapter that may be used to prepare for the quiz, but it will not be graded. All of these problems will be used to construct quizzes and exams. It is very important to understand the problems that are assigned and you are strongly encouraged to work and study in groups or using the discussion board!!


Quizzes: Quizzes will be assigned for each chapter or similar group of chapters. These quizzes will be taken ONLINE only and will not be during class time. You may complete the quizzes in a 30 minute time window using the Respondus Lockdown Browser whenever you are ready by the assigned due date listed for each.

Due Date


Chapters 1,2,3 and 6

1/26 11:59 PM


Chapters 4 and 5

2/14 11:59 PM


Chapters 7, 8, 9

3/2 11:59 PM


Chapters 10, 11, 12

3/23 11:59 PM


Spectroscopy A-C

4/19 11:59PM



 Exams: This course will consist of five in-class exams and one cumulative final exam given on the dates provided. Exam problems will be similar to the assigned problems. Each exam will be taken simultaneously whether in class or on a virtual day. The exam will be timed and must be submitted by the end of the exam time or a penalty of 25% will be imposed. Students taking the exam virtually will either take the exam using Respondus Lockdown Browser or via ZOOM there will be no exceptions. Make up exams will be given only with a verified written medical excuse and verification from the Dean of Students Office.


Exam 1

Friday Jan 29

12:30-1:50 PM

Exam 2

Friday Feb 19

12:30-1:50 PM

Exam 3

Friday March 5

12:30-1:50 PM

Exam 4

Friday March 26

12:30-1:50 PM

Exam 5

Friday April 23

12:30-1:50 PM

Final Exam

Tuesday May 4

11:30-2:00 PM










Grading System:   

5 In-class Exams (100 points each)

500 points

Quizzes (Average of 4 best)

100 points


100 points

Final Exam

200 points


900 points


Grading Scale:


























S/U and Withdrawal Policy: According to University policy, Friday January 15, 2021 is the last day to drop this course. Wednesday, March 10, 2021 is the last day to withdraw from a fall semester course or to declare S/U for the course.


Student code of conduct: As noted in the Student Code of Conduct: Responsibility for good conduct rests with students as adult individuals. Violations of the code of conduct found in the Student Conduct Code Academic Misconduct Policy will be dealt with as described in the policy.




Masking requirement: Winthrop requires that all students adhere to safety practices that will minimize the transmission of COVID-19 within the campus community. Accordingly, students are expected to engage in social distancing and wear a cloth face mask while on campus. Failure to comply with this requirement in the classroom will result in dismissal from the current class meeting. Repeated violations will be reported to the Dean of Students as a violation of the Student Conduct Code. Students with conditions that prohibit the wearing of a face mask should discuss this with their instructor and/or contact the Office of Accessibility to arrange appropriate accommodations.


Online Learning: Any student enrolled in courses at Winthrop regardless of modality (traditional in-person, online, hybrid) is entitled access to all campus resources. These resources include, but are not limited to, admissions counseling, recreational facilities, and health, library, and academic services. Questions regarding access to these resources should be directed to the assigned academic advisor. While attending on your in-person day, you are expected to keep up with all other lectures, assignments and material. All videos will be available on the blackboard course site.


Students with Disabilities Policy: Winthrop University is committed to providing access to education.  If you have a condition which may adversely impact your ability to access academics and/or campus life, and you require specific accommodations to complete this course, contact the Office of Accessibility (OA) at 803-323-3290, or, Please inform me as early as possible, once you have your official notice of accommodations from the Office of Accessibility. This includes your ability to wear a mask for the entire class period or when in the building.


Cheating: Infractions of academic discipline are dealt with in accordance with the student Academic Misconduct Policy which is in the Student Conduct Code in the Student Handbook. Academic misconduct includes, but is not limited to,

providing or receiving assistance in a manner not authorized by the professor in the creation of work to be submitted for academic evaluation including papers, projects, and examinations; presenting, as one’s own, the ideas or words of

another for academic evaluation without proper acknowledgment; doing unauthorized academic work for which another person will receive credit or be evaluated; and presenting the same or substantially the same papers or projects

in two or more courses without the explicit permission of the professors involved. In addition, academic misconduct involves attempting to influence one’s academic evaluation by means other than academic achievement or merit.


Academic Success Center: Winthrop’s Academic Success Center is a free resource for all undergraduate students seeking to perform their best academically.  The ASC offers a variety of personalized and structured resources that help students achieve academic excellence, such as tutoring, academic skill development (test taking strategies, time management counseling, and study techniques), group and individual study spaces, and academic coaching.  The ASC is located on the first floor of Dinkins, Suite 106.  Please contact the ASC at 803-323-3929 or  For more information on ASC services, please visit

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Additional Help: You may access additional tutorials and internet web resources at:




IUPAC rules for nomenclature


Practice writing mechanisms


Org. rxn quizzes/summaries


Practice with synthesis problems


NMR/IR/Mass spec problems















CHEM 301 Class Lecture/Exam Schedule*







Jan. 11

Intro., Ch.1

Atomic structure, bonding

Mar. 8

Ch. 10

Alkene naming, reactions

Jan. 13

Ch. 1

Resonance, hybridization



Ch. 10

Reactions, mechanisms

Jan. 15

Ch. 1, Ch. 2

Polarity, acid-base

Mar. 12

Ch. 10

Reactions, Alkyne naming

Jan. 18


MLK Jr Day

Mar. 15

Ch. 10

Alkyne rxns, synthesis

Jan. 20

Ch. 2, Ch. 3

Structure/acidity, Funct. Grps

Mar. 17

Ch. 11

Redox rxns 

Jan. 22

Ch. 3, Ch. 6

Intermolecular forces, phys. Prop Reactions/energy 

Mar. 19

Ch. 12

 Conj. Dienes, 1,2 v 1.4 rxns

Jan. 25

Ch. 6


Mar. 22

Ch. 12

1,2 v 1,4 rxns, Diels alder

Jan. 27

Ch. 6

Reactions/energy, Review

Mar. 24



Jan. 29

Exam 1 (Ch. 1-3,6)

Mar. 26

Exam 4 (10-12)


Feb. 1

Ch. 4

 Alkanes, nomenclature

Mar. 29

Spectroscopy A

UV/Vis, Mass Spec

Feb. 3

Ch. 4

Alkanes, nomenclature 

Mar. 31

Spectroscopy A/B

Mass Spec/IR

Feb. 5

Ch. 4


Apr. 2

Spectroscopy B


Feb. 8

Ch. 5


Apr. 5

Spectroscopy C

 NMR Intro

Feb. 10

Ch. 5

R/S Enant/Diastereo. Meso/Resolution

Apr. 7

Spectroscopy C


Feb. 12

Ch. 5 Ch. 7

Stereochem calc, SN2 rxn




Spring Break 4 

Feb. 15

Ch. 7

Alcohol substitution, ethers

Apr. 12

Spectroscopy C

Interpretation, splitting

Feb. 17

Ch. 7

Alcohol substitution, ethers, Review

Apr. 14

Spectroscopy C

Interpretation, structure

Feb. 19

Exam 2 (4,5)

Apr. 16

Spectroscopy C

13C NMR, J values

Feb. 22

Ch. 8

Elimination, E2/E1

Apr. 19


Spring Break 5

Feb. 24

Ch. 8

E1/E2 reactions, exceptions

Apr. 21


Feb. 26


Alcohol naming substitution, ethers 



Exam 5 (Spec A-C)


Mar. 1

Ch. 9

Epoxide, redox rxns

Apr. 26

Final Review


Mar. 3


Spring Break 2

May 4

Final exam 11:30


Mar. 5

Exam 3 (7,8,9)





*This is a tentative schedule for lecture and exams (other than the Final Exam). Any changes to this schedule will be announced in class and through email.