Chemistry 106: General Chemistry

(Medicinal Approach)

Dr. T. Christian Grattan (Office Sims 301B)

Summer 2012 - Winthrop University

MTWR 10:00-12:00 PM (SIMS 111)

Textbooks: "General Chemistry," 4^th ed., Donald A. McQuarrie -REQUIRED  

Course objectives:  My goal for this course is to clearly explain the fundamental concepts of general chemistry through the application of medicinal chemistry and related topics.  The students should be able to achieve a working understanding of the structure, function and reactivity for biologically relevant molecules as well as various drug design illustrate the application of general chemistry concepts.   

Office Hours:    MTW 9:30-10 AM, 12-12:30 PM

     or by appointment (323-4927 or grattanc@winthrop.edu)

I will also be accessible to answer questions on email.  You will find that this course is different than any other courses you have taken in college.  It is therefore important to stay on top of the material and get your questions answered as soon as possible.  Please take advantage of my office hours or email to resolve these problems.  

Attendance:  Due to the unique nature of this course, each and every class meeting is important to better understand the material in the text.  The students are responsible for all assignments for the course regardless of absence. 

Homework and Assignments:  Problems will be assigned for each chapter in the text as well as through problem sets.  It is very important to understand the problems that are assigned, as they will be similar to those on the exams.  You are strongly encouraged to work and study in groups!!

Grading System:      3 In-class Exams                                        300 points

  Final Exam                                                  200 points

     500 points

Grading Scale:  The grading scale for this course will be based upon a typical 93-100% (A), 90-93% (A-), 87-89% (B+), 83-86% (B), 80-83 (B-), 77-79% (C+), 70-76% (C), 60-69% (D) < 60%(F) distribution using the total points in the course.

Exams:  This course will consist of three two hour in-class exams and one cumulative final exam given on the dates provided.  Exam problems will be similar to the assigned problems.  Each exam is limited to the allotted class time and the final exam will be limited to two and one-half hours.  Make up exams will be given only with a valid excuse such as a severe personal or family crisis.  

Exam 1          Tuesday, July 17                              10:00 - 12:00 PM

Exam 2          Wednesday, July 25                         10:00 - 12:00 PM

Exam 3          Thursday, August 2                          10:00 - 12:00 PM

Final Exam     Wednesday, August 8                       10:00 - 12:00 PM 

Cheating: Infractions of academic discipline are dealt with in accordance with the student Academic Misconduct Policy which is in the Student Conduct Code in the Student Handbook. Academic misconduct includes, but is not limited to, providing or receiving assistance in a manner not authorized by the professor in the creation of work to be submitted for academic evaluation including papers, projects, and examinations; presenting, as one's own, the ideas or words of another for academic evaluation without proper acknowledgment; doing unauthorized academic work for which another person will receive credit or be evaluated; and presenting the same or substantially the same papers or projects in two or more courses without the explicit permission of the professors involved. In addition, academic misconduct involves attempting to influence one's academic evaluation by means other than academic achievement or merit.

S/U and Withdrawal Policy:  According to University policy, Thursday, July 26, 2012 is the last day to declare S/U for the course.  Tuesday, July 10, 2012 is the last day to drop a fall semester course with an automatic grade of "N".

Students with Disabilities Policy:  Because each student's needs are unique, accommodations are provided based on current, appropriate documentation of disability and needs. Students with disabilities are responsible for 1) identifying themselves to the course instructor, 2) providing documentation, 3) using agreed upon academic accommodations. For further information about services for students with disabilities, call 803/323‑3290 (V/TDD).

Student code of conduct: As noted in the Student Code of Conduct: "Responsibility for good conduct rests with students as adult individuals."  Violations of the code of conduct found in the "Student Conduct Code Academic Misconduct Policy" will be dealt with as described in the policy.

Academic Success Center:  Winthrop's Academic Success Center is a free resource for all undergraduate students seeking to perform their best academically.  The ASC offers a variety of personalized and structured resources that help students achieve academic excellence, such as tutoring, academic skill development (test taking strategies, time management counseling, and study techniques), group and individual study spaces, and academic coaching.  The ASC is located on the first floor of Dinkins, Suite 106.  Please contact the ASC at 803-323-3929 or success@winthrop.edu.  For more information on ASC services, please visit www.winthrop.edu/success.

Winthrop University's Office of Nationally Competitive Awards (ONCA) identifies and assists highly motivated and talented students to apply for nationally and internationally competitive awards, scholarships, fellowships, and unique opportunities both at home and abroad. ONCA gathers and disseminates award information and deadlines across the campus community, and serves as a resource for students, faculty, and staff throughout the nationally competitive award nomination and application process. ONCA is located in Dinkins 222B. Please fill out an online information form at the bottom of the ONCA webpage www.winthrop.edu/onca and email onca@winthrop.edu for more information.

CHEM 106 Class Lecture/Exam Schedule

DATE	Topic
9-July	Lewis structures/VSEPR/Functional Group/ Intro
10-July	Intermolecular Forces
11-July	Solubility + Lipids
12-July	Acid/Base Chemistry - Amino Acids
16-July	Buffers and Drug Solubility
17-July	Exam I
18-July	Intro to Proteins/ Protein Structure
19-July	Enzyme Structure and Function - Kinetics
23-July	Enzymes as Drug Targets
24-July	Drug Receptor Interactions - Thermodynamics
25-July	Exam II
26-July	Nucleic Acids as Drug Targets
30-July	Receptor Structure/Signal Transduction - Electrochem
31-July	Cholinergics
1- Aug	Adrenergics
2-Aug	Exam III
6-Aug	Opioids
7-Aug	Drug Design and Development
8-Aug	Final exam